What is the difference between probiotics and prebiotics?

What is the difference between probiotics and prebiotics?

What is the difference between probiotics, prebiotics, synbiotics, and postbiotics?

summary

 

Probiotics, prebiotics, synbiotics, and postbiotics modulate the composition of the gut microbiota and prevent the risk of dysbiosis. They are a promising therapeutic alternative whose beneficial effects have already been demonstrated by scientific studies.

The gut microbiota 

What is the gut microbiota?

The digestive tract, consisting of the stomach and intestines, is colonized by numerous microorganisms (viruses, bacteria, archaea, and fungi). This ecosystem constitutes the gut microbiota, which evolves in concert with its host. It is involved in many of the body's functions. For example, it protects the body by defending it against pathogens. It is also involved in producing nutrients for the host and in immune responses.

What causes dysbiosis of the gut microbiota? 

An imbalance in the gut microbiota, more commonly known as dysbiosis, contributes to the onset of certain diseases such as neurodegenerative diseases (Alzheimer's, Parkinson's, etc.), metabolic diseases (diabetes, obesity, etc.), cancers, allergies, etc. This is why restoring its balance is now essential for the host to improve their health.

How can dysbiosis be prevented? 

A diet enriched with probiotics, prebiotics, synbiotics, and postbiotics is beneficial for the composition and diversity of the gut microbiota, as well as its balance with the body. It limits the risk of dysbiosis.

probiotic

What are probiotics, prebiotics, synbiotics, and postbiotics?

The term biotic, from the Latin bioticius meaning pertaining to life, refers to all factors related to the activity of living beings. Probiotics, prebiotics, synbiotics, and postbiotics modulate the composition of the ecosystem and its activity. They are naturally present in certain foods and are beneficial to those who consume them. They can also be taken as dietary supplements.

probiotics

What is a probiotic?

 

Definition of probiotics 

Probiotics are live microorganisms that, when ingested in sufficient quantities, have beneficial effects on the individual. They combat the colonization and development of pathogenic microorganisms in the intestine.

How to choose your probiotics? 

A compound is considered a probiotic if and only if it meets a number of criteria. It must be gastro-resistant, meaning that it must not break down before reaching the colon, where it performs its functions. In addition, its effectiveness on health must have been scientifically studied and cannot be generalized to all strains of the same species.

Health benefits of probiotics 

Probiotics have many health benefits. First, they promote the growth of good bacteria at the expense of pathogenic bacteria from the environment or diet and improve the effectiveness of the immune system.

They play a role in certain conditions such as inflammatory bowel disease and irritable bowel syndrome by reducing symptoms. They may also reduce the incidence of colon cancer. They have positive effects on episodes of diarrhea, particularly on their duration. They improve the digestion of lactose and sucrose in cases of lactose and sucrose intolerance. Finally, certain products of their metabolism may have antibiotic, anti-carcinogenic, and immunosuppressive properties.

Which probiotic should you take to rebuild your intestinal flora?

Among the most effective probiotics for rebuilding your intestinal flora are bacteria such as Lactobacillus, Bifidobacterium, Streptococcus, Bacillus, Enterococcus, and yeasts such as Saccharomyces boulardii, which can be found in various foods such as dairy products, kefir, kombucha, soy products, sauerkraut, brewer's yeast, etc.

healthy

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Health benefits of prebiotics 

Prebiotics are extremely beneficial to the host. First, they promote the growth of good intestinal bacteria such as Bifidobacteria, Lactobacilli, etc., to the detriment of pathogenic bacteria. In addition, their positive effects have been demonstrated in stimulating the immune system, increasing nutrient absorption, reducing blood cholesterol levels, and preventing carcinogenesis.

Examples of prebiotics 

There are various sources of prebiotics, such as inulin, FOS (fructo-oligosaccharides), GOS (galacto-oligosaccharides), and fructans, which can be found in vegetables (garlic, artichokes, asparagus, beets, broccoli, cabbage, leeks, endives, fennel, green beans, tomatoes, etc.), legumes (flageolet beans, black beans, red beans, lentils, chickpeas, etc.), fruits (bananas, apples, dried fruit, dates, figs, grapefruit, pears, etc.), roots (chicory, parsnips, and Jerusalem artichokes), oilseeds (almonds, walnuts, pistachios, etc.), and seeds (oats, whole wheat, flax, barley, and rye).

dietary

What is a symbiotic?

Definition of synbiotics 

Symbiotics are substances that contain both a probiotic and a prebiotic that work synergistically. The prebiotic component selectively stimulates the growth of the probiotic microorganism and enables it to survive in the digestive tract.

How to choose your symbiotics?

When choosing a symbiotic, there are a number of criteria to consider. First, it is important to pay attention to the diversity of strains and the quantity of microorganisms ingested. Finally, it is essential that they are gastro-resistant in order to colonize the colon.

Health benefits of synbiotics 

In the case of symbiotic substances, the combination of prebiotics and probiotics allows the probiotics to survive and increase their health benefits for the host. Symbiotics combine the benefits of probiotics and prebiotics. Finally, it is important to note that synbiotics do not have a specific effect on overall health. The benefits of synbiotics are rather associated with the specific combination of probiotics and prebiotics found in a synbiotic supplement.

Examples of synbiotics 

Among the most commonly used symbiotics in human nutrition are the combinations listed in the table below:

example

What is a postbiotic?

Definition of postbiotics

Finally, postbiotics are compounds produced by the activity of microorganisms. The metabolization of prebiotics by probiotics generates metabolites such as short-chain fatty acids (SCFAs), enzymes, and substrates that are extremely beneficial to the body.

Enzyme: a molecule that contributes to the progress of a biochemical reaction

Substrate: substance on which the enzyme acts during the biochemical reaction

Fatty acid: a component of lipids (or fats)

Health benefits of postbiotics

In addition to improving overall health, postbiotics are effective in preventing and limiting the symptoms of several diseases. They are most commonly used in infants to reduce colic and in people with severe inflammatory bowel disease such as Crohn's disease or ulcerative colitis. They are also effective in cases of atopic dermatitis (or atopic eczema). However, they are currently only used in specific clinical contexts.

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Conclusion

In conclusion, probiotics, prebiotics, synbiotics, and postbiotics offer numerous health benefits. They prevent the risk of dysbiosis and therefore the disorders that can be associated with it. To reap the full benefits, it is essential to eat a healthy and varied diet rich in probiotic and prebiotic foods (Shido) or to take dietary supplements enriched with these nutrients.

Sources:

Paulina Markowiak, Katarzyna Slizewska. Effects of Probiotics, Prebiotics, and Synbiotics on Human Health. Nutrients. 2017. 

Carrie A. M. Wegh, Sharon Y. Geerlings, Jan Knol, Guus Roeselers, Clara Belzer. Postbiotics and Their Potential Applications in Early Life Nutrition and Beyond. Internal Journal of Molecular Sciences. 2019.

S.M. Schneider. Probiotics. Medicine of Metabolic Diseases. 2008

Géraldine Favre. Prebiotics and probiotics: do they have real health benefits? The role of pharmacists in advising customers in pharmacies. Pharmaceutical Sciences. 2004.

Ravi Mangal Patel, MD and Patricia Wei Denning, MD. Therapeutic Use of Prebiotics, Probiotics, and Postbiotics to Prevent Necrotizing Enterocolitis: What is the Current Evidence? Clin Perinatol. 2013.

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Acting on short-chain fatty acid production

Acting on short-chain fatty acid production

Acting on your production of short-chain fatty acids

The gut microbiota

Our health ally

The body evolves in symbiosis with the ecosystem it harbors in the digestive tract. It is composed of a multitude of microorganisms (viruses, bacteria, archaea, fungi) and forms the gut microbiota. Each of these bacteria plays a key role in many vital functions of the body and also in maintaining good health. However, if the balance is disrupted, bacteria that were initially beneficial to health can become harmful and lead to disorders such as neurodegenerative diseases (Alzheimer's, Parkinson's, etc.), metabolic diseases (diabetes, obesity), cancers, and allergies.

Factors that alter the gut microbiota 

The gut microbiota develops from birth until around the age of two and a half. After that, it is considered stable and its composition will only change due to certain factors such as illness, stress, medication, health, diet, geographical location, etc. Under the influence of these factors, the bacterial composition may change.

How can we influence the gut microbiota? 

Today, a link has been established between diet and the bacterial composition of the gut microbiota. It is therefore important to eat a varied and balanced diet in order to optimize your microbiota and enjoy its benefits. For example, it is recommended to increase your intake of dietary fiber at the expense of simple carbohydrates. In addition to being filling and beneficial for intestinal transit, fiber reduces the risk of diabetes, cancer, and cardiovascular disease. Finally, it also nourishes good intestinal bacteria. 

 

Diet

Carbohydrates, more commonly known as sugars, are molecules whose function is to provide energy to the body in the form of calories. There are two types of carbohydrates: simple (or monosaccharides) and complex (or polysaccharides). Simple carbohydrates such as glucose, fructose, and galactose are non-hydrolyzable molecules, meaning they cannot be broken down into smaller molecules.

Complex carbohydrates, on the other hand, are formed by the linking of simple carbohydrates. These include disaccharides such as lactose and sucrose, which are composed of two simple carbohydrates, and polysaccharides (starch, cellulose, glycogen, etc.), which are composed of more than two simple carbohydrates. Only simple carbohydrates and disaccharides in complex carbohydrates have sweetening power. Polysaccharides do not.

 

Diet

Dietary fiber is a complex carbohydrate of plant origin that is neither digested nor absorbed by the body. There are two types of fiber: soluble fiber and insoluble fiber. Fiber is naturally present in plant-based foods, but its distribution varies. Vegetables (artichokes, beets, carrots, broccoli, cabbage, etc.), legumes (beans, lentils, chickpeas, etc.), whole grains (oats, spelt, brown rice, etc.), fruits (apples, pears, oranges, grapefruit, etc.) and dried fruits (dates, prunes, etc.) are excellent sources.

Digestion of dietary fiber

Once ingested, dietary fiber passes through the digestive tract to the colon without being digested or absorbed. It is in the colon that it first undergoes hydrolysis (or dissociation) by enzymes and then fermentation by bacteria, releasing short-chain fatty acids. Some of these acids perform their functions in the intestine, while others migrate and act throughout the body. 

 

A

Short-chain fatty acids 

 

What are SCFAs? 

Short-chain fatty acids (SCFAs) are a subset of fatty acids synthesized by the gut microbiota during the fermentation of non-digestible polysaccharides such as dietary fiber. Put simply, they are molecules produced by good gut bacteria during the fermentation of food. There are several types, such as acetate, butyrate, lactate, propionate, and succinate, which vary in proportion and function. Acetate, butyrate, and propionate are the most common. Each plays an important role in maintaining health and in the development of disease.

Where do SCFAs act? 

Once produced, SCFAs can remain in the colon and be used by intestinal cells or be transported into the bloodstream to act on other organs. The production of SCFAs is influenced by various factors. It depends on the number of bacterial species present in the gut microbiota. The source of dietary fiber and transit time also play a role.

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What are the health effects of SCFAs? 

AGCCs are now recognized as mediators of the beneficial effects of dietary fiber and gut microbiota on host health. First, they play a key role in maintaining intestinal health. They improve the integrity of the intestinal barrier by regulating pH and mucus production and providing the energy necessary for epithelial cells to perform their functions. They also modulate inflammatory and immune responses.  They regulate immune cell function and lymphocyte differentiation. Lymphocytes are white blood cells that are part of the immune system and protect the body against attacks (bacteria, viruses, diseases, etc.). They also limit the proliferation of tumor cells. In addition, they act on skeletal muscles by modulating their function and exercise capacity. Finally, they prevent the risk of gastrointestinal disorders, hypertension, insulin resistance, obesity, cancer, and cardiovascular disease.

How can you find out your AGCC level? 

It is now possible to analyze your gut microbiota. In addition to detecting the depletion of bacterial biodiversity associated with the risk of dysbiosis, the analysis also detects short-chain fatty acids.

How can you increase your SCFA levels? 

As diet is the main factor influencing the amount of short-chain fatty acids, it is now essential to include fiber-rich foods in your diet to stimulate their production. The higher your fiber intake, the more SCFAs will be produced.

Focus

Focus on butyrate  

A fiber-rich diet is extremely beneficial to health. Increasing butyrate levels has several benefits. In addition to being the main source of energy for epithelial cells, it plays a key role in preventing cancer and inflammatory bowel disease. Furthermore, butyrate supplementation has been shown to reduce the risk of obesity.

Focus on succinate

Succinate, on the other hand, appears to have negative effects. High levels of succinate are found in the intestinal lumen in patients with dysbiosis or inflammatory bowel disease. However, its involvement remains to be confirmed.

In conclusion, it is essential to ensure sufficient dietary fiber intake to enable the microbiota to produce short-chain fatty acids and thus promote good health. In addition to their benefits for the microbiota, fibers are essential for the body. They act as our allies for optimal well-being and to limit the risk of developing certain diseases. Short-chain fatty acids are considered key mediators between diet, gut microbiota, and health. Nahibu, a player in the food industry of tomorrow, offers a gut microbiota analysis solution that measures its diversity and detects SCFAs.  

 

Sources:

Jian Tan, Craig McKenzie, Maria Potamitis, Alison N Thorburn, Charles R Mackay, Laurence Macia. The role of short-chain fatty acids in health and disease. 2014.

Sean M McNabney, Tara M Henagan. Short Chain Fatty Acids in the Colon and Peripheral Tissues: A Focus on Butyrate, Colon Cancer, Obesity and Insulin Resistance. 2014.

Yao Yao, Xiaoyu Cai, Weidong Fei, Yiqing Ye, Mengdan Zhao, Caihong Zheng. The role of short-chain fatty acids in immunity, inflammation and metabolism. 2020.

James Frampton, Kevin G Murphy, Gary Frost, Edward S Chambers. Short-chain fatty acids as potential regulators of skeletal muscle metabolism and function. 2020.

E E Blaak, E E Canfora, S Theis, G Frost, A K Groen, G Mithieux, A Nauta, K Scott, B Stahl, J van Harsselaar, R van Tol, E E Vaughan, K Verbeke. Short chain fatty acids in human gut and metabolic health. 2020.

Julia M W Wong, Russell de Souza, Cyril W C Kendall, Azadeh Emam, David J A Jenkins. Colonic health; fermentation and short chain fatty acids. 2006.

Sathish Sivaprakasam, Puttur D Prasad, Nagendra Singh. Benefits of short-chain fatty acids and their receptors in inflammation and carcinogenesis. 2016.

 

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What is a healthy and balanced diet?

What is a healthy and balanced diet?

What is a healthy and balanced diet? 

According to the World Health Organization, chronic diseases linked to diet, such as obesity, diabetes, cardiovascular disease, and cancer, are the leading cause of death worldwide. The influence of our diet on our health is becoming increasingly well known, and the risk of developing these diseases can now be reduced by adopting a healthy diet. A varied and balanced diet is essential for the body. It enables it to function optimally and reduces the risk of developing diseases.  

How important is a healthy diet? 

Eating is a vital need. The nutrients provided by food are essential for the body. They are divided into energy-producing and non-energy-producing nutrients. Energy nutrients, represented by macronutrients (fats, carbohydrates, proteins), provide the body with energy in the form of calories, while non-energy nutrients, or micronutrients (minerals, vitamins, amino acids, enzymes, etc.), enable the body's biological processes to function properly. If nutrient intake is insufficient, nutritional deficiencies occur, i.e., an imbalance between nutrient intake and requirements, which often has significant consequences for health.

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What does the human body need?

To function properly, the body needs a sufficient and regular supply of energy and nutrients. Nutritional needs include water, energy, nutrients, vitamins, and minerals. They enable the body to develop, renew tissue, and maintain good overall physical and mental health. These needs are normally met by a varied and balanced diet.

An appropriate calorie intake 

Daily calorie intake depends on several factors such as gender, age, body size, and physical activity. For women, the recommended calorie intake is approximately 2,000 to 2,200 kilocalories (kcal) per day, depending on age and physical activity. For men, it is 2,500 to 2,700 kcal. If you exercise, your calorie intake should be increased in proportion to the intensity of the activity. For example, during very intense physical activity, calorie intake can reach 2600 kcal for women and 3400 kcal for men. The amount of calories needed each day also depends on age. Calorie intake decreases with age. It is important to note that insufficient calorie intake can cause serious health problems. It can lead to micronutrient deficiencies and thus to numerous hormonal and bone disorders, etc.

Adequate nutrient intake 

Proteins 

Proteins are made up of chains of amino acids. There are 22 different amino acids, 8 of which are known as essential. This means that since the body cannot synthesize them, they must be obtained from food.  The others are synthesized by the body using the proteins present. To ensure an adequate intake of amino acids, the proteins ingested must be sufficient and varied. Proteins are involved in many structural, metabolic, and immune functions.

Carbohydrates 

Carbohydrates, more commonly known as sugars, are responsible for providing the body with energy in the form of calories. There are two types of carbohydrates: simple and complex.

Foods are differentiated according to their glycemic index, which indicates a food's ability to raise blood sugar levels (glycemia). The higher the index, the faster blood sugar levels rise. A high glycemic index requires the pancreas to release insulin to lower blood sugar levels; insulin converts glucose into glycogen, which is used as energy. If there is excess glycogen, glucose is converted into fat, which is why sugar can cause weight gain.

Dietary fiber is a complex carbohydrate of plant origin that is neither digested nor absorbed by the body. Fiber is naturally present in plant-based foods.

Some simple carbohydrates, such as fructose, occur naturally in fruits, while others, such as glucose and galactose, are added to foods before they reach our plates. Regardless of their origin, simple carbohydrates are responsible for sweetness and provide the body with immediate energy.

Complex carbohydrates are formed by a chain of simple sugars and are found in legumes, tubers, and cereals. Unlike simple carbohydrates, they provide the body with energy more gradually. In addition, they are absorbed by the body much more slowly.

Lipids 

Lipids are more commonly known as fats and are essential for the body to function properly. They are divided into saturated fatty acids, unsaturated fatty acids, and trans fatty acids. Lipids require special attention because many of them should be limited. Saturated fatty acids provide energy and vitamins and are part of the composition of cell membranes. Unsaturated fatty acids are broken down into omega-3, 6, and 9. Omega-3 and 9 are to be favored, while omega-6, if consumed in excess, impacts the functioning of omega-3 and 9. Finally, trans fatty acids result from a process of hydrogenation of unsaturated fatty acids carried out in the food industry to increase their stability and shelf life. They are not natural. These differences therefore require us to pay attention to the type of fat we consume in order to favor the good and limit the bad. For example, it is recommended to reduce trans fatty acid consumption as much as possible, as they are associated with an increased risk of cardiovascular disease.

Minerals 

Minerals include major minerals and trace elements, both of which are essential for the body as they are involved in many chemical reactions. Major minerals include magnesium, sodium, potassium, and calcium.

Vitamins 

Vitamins are essential for the body to function properly because they are involved in many functions. They are obtained exclusively from food. The necessary daily intake varies from person to person. There are 13 vitamins that play a role in various functions: vitamins A, C, D, E, K, B1, B2, B3, B5, B6, B8, B9, and B12.

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What constitutes a balanced diet? 

Eating a varied and balanced diet means eating well and in quantities that allow the body to function properly.

First of all, since no single food can meet the body's daily nutritional needs on its own, it is recommended to combine several foods in a meal. This increases the number of nutrients that will be delivered to our cells during digestion. During digestion, food is broken down by enzymes into macronutrients and micronutrients and transported to the organs via the bloodstream.

Eating well also means choosing foods that are good for your health over those that are less healthy. In particular, it is recommended to increase your consumption of fruits, vegetables, legumes (lentils, beans, chickpeas, split peas, broad beans, etc.), unsalted nuts (walnuts, almonds, etc.) and to opt for homemade foods as much as possible to limit the potential intake of additives that have no nutritional value.

Balanced

You should reduce your intake of alcohol, sugary foods and drinks, salty foods, meat (pork, beef, veal, lamb, mutton), charcuterie, and products with a Nutri-score between D and E. The Nutri-score assesses the nutritional quality of a product, from A, a very favorable product in terms of nutrition, to E, an unfavorable product, based on its nutrient composition, foods to favor (fiber, fruits, vegetables, proteins), and foods to limit (sugar, salt, calories, saturated fatty acids).

Finally, it is important to prioritize whole, unrefined foods: whole grain bread, cereals, and starchy foods, as well as healthy fats found in oily fish (salmon, tuna, mackerel, etc.) and vegetable oils, particularly rapeseed and olive oil. It is also important to note that a balanced diet is not determined by a single meal, but is built up over several meals. This is why it is entirely possible to restore balance with lighter, more balanced meals after a heavier, higher-calorie festive meal.

Put simply, to provide the body with everything it needs, your plate should be composed as follows: ½ vegetables, ¼ protein, and ¼ starchy foods.

When it comes to vegetables, it is best to choose fresh, seasonal produce, as these will be richer in nutrients and free from preservatives and other additives that can be found in canned vegetables. It is also recommended to vary your vegetable intake to fully benefit from the different health benefits they can provide.

Daily protein intake depends on body size. It is recommended to consume 1 gram of protein per kilogram of body weight, or 60 grams for a person weighing 60 kilograms. As with vegetables, it is important to vary your sources of protein between plant and animal sources.

The last quarter of the plate is reserved for starchy foods. However, this may vary depending on the individual's physical activity and energy expenditure. Among starchy foods, it is advisable to consume those with a low or moderate glycemic index rather than those with a high glycemic index, as the latter promote fat storage.

In addition to this, there are portions of fruit, healthy fats, and possibly dairy products. Fruit is a source of antioxidants, vitamins, minerals, and fiber, which are essential for good health. As for fats, not all of them should be avoided. However, it is important to favor the consumption of healthy fats and limit unhealthy fats.

Physical

Not forgetting physical activity 

In addition to eating a balanced diet, it is essential to engage in regular physical activity and limit sedentary behavior as much as possible, as it poses health risks. Physical activity is the ultimate health ally: it contributes to daily well-being and, even more importantly, helps maintain good overall health. It is also associated with a reduction in disease.

What's more, playing sports releases endorphins in the brain, in proportion to the intensity, duration, and nature of the physical activity. More commonly known as happiness hormones, endorphins bring about feelings of pleasure.

Conclusion

In conclusion, it is essential to have a varied and balanced diet to enable the body to function properly and also to engage in regular physical activity. However, as Paracelsus said, Everything is poison and nothing is without poison; only the dose makes something not a poison. Balanced and varied does not mean restrictive; you can eat everything, it's all about quantity. Nevertheless, it is important to favor healthy foods such as fruits, vegetables, legumes, nuts, etc., and limit sugary and salty foods, processed meats, red meat, alcohol, fats, etc.

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Sources: 

 

https://www.mangerbouger.fr/

Nutrition and health. INSERM. Available at: https://www.inserm.fr/information-en-sante/dossiers-information/nutrition-et-sante

Balanced diet. Eating well for well-being. French Cardiology Federation. Available at: https://www.fedecardio.org/sites/default/files/image_article/BROCHURE-Alimentation.pdf

Nutritional requirements and dietary intake for adults. Collegiate Society of Hepato-Gastroenterology Specialists. Available at this link.

Nutritional recommendations for ages 18 to 75. VIDAL. Available at: https://www.vidal.fr/sante/nutrition/equilibre-alimentaire-adulte/recommandations-nutritionnelles-adulte.html

What you need to know about carbohydrates. French Cardiology Federation. Available at: https://www.fedecardio.org/Je-m-informe/Je-mange-equilibre/ce-qu-il-faut-savoir-sur-les-glucides

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A

What role does sugar play in obesity?

What role does sugar play in obesity?

What role does sugar play in obesity?

Obesity is now a global epidemic, and its prevalence has been increasing since 1980. In 2014, there were more than 1.9 billion overweight adults, 600 million obese adults, and 41 million overweight or obese children under the age of 5. France is following the same trend as the rest of the world. Body mass index (BMI) is calculated based on an individual's weight and height (weight (in kg) / (height (in cm))²) and is used to assess body size.

A score between 25 and 30 indicates overweight, and between 30 and 40 indicates obesity. A score of 30 corresponds to moderate obesity and 40 to morbid obesity. Beyond the problems of excess weight, obesity is a major risk factor for many diseases, including diabetes, cardiovascular disease, fatty liver disease, dyslipidemia, cancer, etc.  Obesity is most often the result of an energy imbalance between calories consumed and calories expended, and an increase in the consumption of foods high in sugar and fat at the expense of healthier foods.

Today, sugar is an integral part of our diet and its consumption is only increasing, even among young children. It is estimated that the average French person consumes between 30 and 35 kilograms of sugar per year, compared to 26 in 1950 and 5 in 1850.  While sugar should not be demonized because it provides the body with necessary energy, its overconsumption is harmful to health. The consequences of excessive sugar consumption are numerous and include obesity and other metabolic disorders.

Overweight

What is sugar? 

Carbohydrates, more commonly known as sugars, are molecules whose function is to provide energy to the body in the form of calories. There are two types of carbohydrates: simple (or monosaccharides) and complex (polysaccharides and disaccharides). Simple carbohydrates such as glucose, fructose, and galactose are non-hydrolyzable molecules, meaning they cannot be broken down into smaller molecules. Complex carbohydrates, on the other hand, are formed by linking simple carbohydrates together. These include disaccharides such as lactose and sucrose, which are composed of two simple carbohydrates, and polysaccharides (starch, cellulose, glycogen, etc.), which are composed of more than two simple carbohydrates. Only simple carbohydrates and disaccharides in complex carbohydrates have sweetening power. Polysaccharides do not.  

excess

What sugars and in what forms?

Sugars are now ubiquitous in our diets. They come in several forms, found naturally in fruits and honey, and also in the form of refined sugar in processed products such as cookies, drinks, candies, etc. Processed foods contain the highest amounts of sugar. Sugar is very often added to these foods during manufacturing.

The most common sugars include the following:

Sucrose, or table sugar, is the best known. It is the sugar par excellence and the one used in the food industry for making cakes, drinks, etc. It consists of glucose and fructose and comes from sugar beets or sugar cane. It has a sweetness rating of 100, which is the maximum.

Sweetness is the sweetening value of one chemical compound compared to another. Sucrose is most often used as the reference solution, with a sweetness value of 100.

Glucose is also found naturally in the body. The food industry extracts it from starch through hydrolysis. It has a sweetness rating of 70.

Fructose is a natural sugar found in fruits and honey. It is also found in significant quantities in ultra-processed foods. The food industry extracts it and adds it to foods. It has a high sweetening power of between 130 and 150.

Glucose syrup is produced by breaking down starch. It has a low sweetening power of 27 to 55.

Finally, glucose-fructose syrup, or isoglucose, or high-fructose corn syrup (HFCS), is produced by processing glucose syrup and has a sweetness similar to that of sucrose. It contains a proportion of fructose and is widely used by manufacturers.

Although they have a similar caloric value, all these sugars differ in their sweetness, their physical and chemical characteristics, and therefore their effects on health. Sugars added to foods and beverages during manufacturing by industry or by consumers are the most harmful to health, and their consumption continues to rise. They are believed to be partly responsible for the global obesity epidemic.

 

sugar

How are sugars digested and absorbed? 

Once swallowed, carbohydrates undergo a number of physical and chemical transformations. As they pass through the mouth and then the digestive tract, they are broken down into small molecules. This is a necessary step, as only simple sugars can be absorbed by the intestine.

First, complex carbohydrates are broken down into simple carbohydrates consisting of fewer units when they come into contact with the amylase contained in saliva. Then, once in the intestine, pancreatic amylase and other even more specific enzymes such as lactase or saccharase take over and break down the carbohydrates into even smaller units. Ultimately, this produces relatively small sugars such as glucose, fructose, and galactose, which can be absorbed by the cells of the intestine and thus enter the bloodstream to provide sufficient energy to all the organs of the body. Glucose is the main source of energy for cells.

The intestinal wall contains intestinal cells, called enterocytes, which use specific transporters to move the reduced sugars from the digestive tract into the bloodstream.

Once in the blood, glucose increases blood sugar levels. Blood sugar levels correspond to the amount of glucose in the blood and are measured in grams per liter of blood. When fasting, the value should be between 0.8 and 1 gram per liter of blood. If there is too much glucose, this is called hyperglycemia, while if there is not enough, it is called hypoglycemia. Blood sugar levels are controlled simultaneously with the release of hormones by the pancreas, small intestine, and colon. Hormones are molecules produced by an organ that are released into the bloodstream to transmit a message to a target organ. The pancreas releases insulin and glucagon, while the small intestine and colon release GLP-1. Insulin is a hypoglycemic hormone produced by the pancreas that is released into the blood after a meal to reduce blood sugar levels, while glucagon is a hyperglycemic hormone that is released to increase blood sugar levels. Finally, GLP-1 is a hormone in the colon whose role is to increase insulin secretion after a meal.

Once in the blood, glucose travels to various organs. The liver stores glucose for the body in the form of glycogen and is responsible for supplying glucose to cells. Muscles store glucose in the form of glycogen for their own use. Adipose tissue, or fat cells, also stores glucose, but in the form of triglycerides, more commonly known as fat. Finally, the brain also consumes glucose, using 60% of the body's glucose. Since it cannot store it, the liver supplies it with glucose.

When blood sugar levels are low, the pancreas releases glucagon, which increases blood sugar levels by drawing on the endogenous glucose reserves stored in the organs. Conversely, when blood sugar levels rise, the insulin released promotes the storage of glucose in the organs in the form of glycogen, ultimately reducing blood glucose levels.

 

excessive

What are the consequences of excessive sugar consumption?

Simple carbohydrates are most often referred to as fast sugars because they cause a rapid increase in blood sugar levels. Overconsumption leads to a loss of insulin sensitivity, which then becomes insufficient to bring blood sugar levels back down to their baseline. The glucose then remains in the bloodstream and is recovered and stored by adipose tissue in the form of fat. This leads to weight gain and, even more so, to obesity.

Beyond disrupting the system, overconsumption has significant consequences for the gut microbiota. It promotes dysbiosis, an imbalance in the gut microbiota, and is likely to cause a decline in bacterial diversity.

Overconsumption is also harmful to the brain. A 2012 study in rodents showed that a high-fructose diet impacted memory, learning, and neural communication. These observations have been replicated in humans, and the impact on brain function is dependent on sugar consumption. The higher the consumption, the greater the impact on cognitive function.

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Should we stop eating sugar? 

Nowadays, it is more important than ever to review your sugar intake. ANSES recommends that adults consume no more than 100 grams of sugar and no more than one sugary drink per day. Above this level, sugar consumption has an impact on the body. However, as glucose is the body's main source of energy, it should not be eliminated entirely.

It is therefore important to find the right balance, to opt for natural sugars and to be mindful of hidden sugars and sweeteners. The latter give a sweet taste to food and drink and were developed to combat diabetes and obesity. They are mostly synthetic and are characterized by their high sweetening power and lack of calories. However, it has now been shown that they contribute to weight gain and other metabolic disorders. The consumption of non-caloric artificial sweeteners leads in particular to the development of glucose intolerance and dysbiosis of the intestinal microbiota. Glucose intolerance occurs when the body becomes insensitive to insulin and no longer assimilates glucose properly. This results in an increase in blood glucose and can in some cases lead to the onset of diabetes. Reducing sugar consumption should not be done in favor of these sweeteners, which do not appear to be as beneficial to health as they seem.

 

Sources:

The different types of sugars. Nutrition. GOOD TO EAT, GOOD TO KNOW. Available at: https://www.lanutrition.fr/les-differents-types-de-sucres

Sugars in food. ANSES. Available at: https://www.anses.fr/fr/content/sucres-dans-l%E2%80%99alimentation

Sugar and food. PLANET VIE. Available at: https://planet-vie.ens.fr/thematiques/sante/sucre-et-alimentation

Digestion and assimilation of carbohydrates. PENSER SANTE. Available at: https://www.pensersante.fr/digestion-et-assimilation-des-glucides

Lenny R. Vartanian, PhD, Marlene B. Schwartz, PhD, and Kelly D. Brownell, PhD. Effects of Soft Drink Consumption on Nutrition and Health: A Systematic Review and Meta-Analysis. AJPH. 2006.

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Which foods are richest in vitamin C?

Which foods are richest in vitamin C?

Top 10 foods richest in vitamin C.

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What is vitamin C used for?

Vitamins are essential for the body, enabling it to function properly. Once obtained from food, they play a role in many functions. Among them, vitamin C, or ascorbic acid, plays a major role in protecting the body against viral and bacterial infections and free radicals. It also plays a role in protecting blood vessels and in healing processes. Finally, it promotes the absorption of iron from plants by the body. 

What are our vitamin C requirements?

According to ANSES, the daily intake of vitamin C should be 110 mg for adults, equally for men and women.

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Where can you find vitamin C?

Plants contain vitamin C. Therefore, regular consumption of fruits and vegetables generally covers your vitamin C needs.

It is also found in certain industrial products under the name ascorbic acid or E300, where it is used as a preservative.

The 10 plants with the highest vitamin C content include:

Acerola cherry

The acerola cherry, more commonly known as the West Indian cherry or acerola, is a plant that comes from Latin America and tropical regions. Acerola produces red cherry berries that are very rich in vitamin C (2850 mg per 100 g). It also contains vitamins B and A and other minerals such as magnesium, potassium, phosphorus, iron, and calcium. In addition to the fruit, it can be found in powdered supplement form, which is made by dehydrating acerola cherry juice.

Guava 

Guava is a fruit from the guava tree that contains an average of 228 mg of vitamin C per 100 g of fruit. It is also rich in vitamin A and polyphenols, which give it antioxidant properties. These three elements combined enable it to significantly protect the body against free radicals and the aging they cause. Finally, due to its high fiber content, guava ensures good digestion.

Blackcurrant

Blackcurrants, the fruit of the blackcurrant bush, are also a significant source of vitamin C. Blackcurrants contain 181 mg of vitamin C per 100 g. They are also a source of vitamin E and minerals such as potassium. The fiber, cellulose, hemicellulose, lignin, and pectin it contains stimulate digestion, promote satiety, and are associated with a reduction in bad cholesterol in the blood. Finally, its low glycemic index does not cause a rapid increase in blood sugar.

Chili pepper

Chili peppers come from a plant in the Solanaceae family. There are several varieties, depending on their color and flavor, which can be more or less pronounced. Among these, we also find sweet peppers. Beyond their spicy flavor, chili peppers have high nutritional value. They are rich in vitamins C, A, B6, E, and K, as well as trace elements such as copper, iron, manganese, magnesium, and potassium. They contain 155 mg of vitamin C per 100 g. Finally, their flavonoid content protects the body against free radicals, while their capsaicin content has a beneficial effect on digestion, inflammation, and infections. They are also associated with increased satiety.

Bell pepper

Whether raw or cooked, bell peppers are also nutritionally beneficial. In addition to being low in calories, they are a source of vitamins A, K, C, and B, minerals, antioxidants, and fiber. This allows them to stimulate the body's immune defenses and, thanks to their fiber content, facilitate digestion. However, when eaten raw, bell peppers can cause reflux and bloating. They contain 126 mg of vitamin C per 100 g.

Brussels sprouts

Brussels sprouts contain 103 mg of vitamin C per 100 g, in addition to remarkable amounts of vitamins B and K and minerals such as calcium and potassium. They also contain antioxidants and fiber. They combat the effects of aging caused by free radicals.

Kiwi

Kiwis are also a source of vitamins C, K, B9, and E, as well as copper and potassium. They contain 81.9 mg of vitamin C per 100 g of fruit. They can therefore play a role in protecting the body against infections and free radicals. In addition, each fruit has a fiber content of approximately 2.4 g.

Strawberry

Strawberries are the ultimate summer fruit with numerous health benefits. In addition to being low in calories (38.6 kcal per 100 g of fruit), they are rich in water and fiber. They stimulate intestinal transit and reduce bloating. They also contain vitamins C (54 mg per 100 g) and B9, as well as minerals such as manganese. Finally, they are a significant source of flavonoids, which give them important antioxidant properties.

Kale

Kale contains 41 mg of vitamin C per 100 g. In addition to being low in calories, it is also rich in minerals, antioxidants, and fiber (4.9 g per 100 g). It promotes digestion and is a real health ally for the body.

Broccoli

Broccoli is packed with vitamins B, C (23.9 mg per 100 g), E, and K, as well as minerals such as potassium, calcium, magnesium, copper, iron, and zinc. It is also rich in antioxidants and fiber, which help regulate digestion and promote satiety. Finally, it contains nearly 90% water and is low in calories.

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It is important to note that vitamin C is fragile. It deteriorates quickly when exposed to water, heat, air, and light. To fully enjoy its benefits, it is recommended to consume fruits and vegetables that are as fresh as possible and to avoid long cooking times.

Sources:

Vitamin C or ascorbic acid. ANSES. Available at: https://www.anses.fr/fr/content/vitamine-c-ou-acide-ascorbique

Ciqual. Food composition table. ANSES. Available at: https://ciqual.anses.fr/

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Which foods are highest in fiber?

Which foods are highest in fiber?

Which foods are highest in fiber?

Fiber is a complex carbohydrate of plant origin that is neither digested nor absorbed by the body. There are two types of fiber: soluble fiber and insoluble fiber.

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What is fiber good for?

Insoluble fiber increases stool volume and stimulates intestinal transit. It promotes satiety. Soluble fiber lowers cholesterol levels and improves carbohydrate absorption. It also reduces blood sugar and insulin levels after meals. Finally, they stimulate the growth of good intestinal bacteria and are associated with a reduced risk of cardiovascular disease.

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What are our fiber requirements? 

ANSES recommends consuming 30 grams of fiber per day, equally for men and women. On average, adults consume 17.5 grams of fiber per day. It is therefore important to include fiber-rich foods in your diet to increase your fiber intake.

 

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Where can fiber be found?

Fiber is naturally present in food, but some types of food contain more than others.

Grains and seeds

Cereals and seeds are excellent sources of fiber. Corn bran contains 79 grams of fiber per 100 grams and wheat bran contains 42 grams. There is also rice bran (21 grams per 100 grams), oat bran (16.7 per 100 grams), etc. Chia seeds contain 34.4 grams and flax seeds contain 27.3 grams per 100 grams. Bran and other whole grains such as rice and wheat are sources of insoluble fiber and quickly make you feel full by swelling with water during digestion. Oats and barley provide soluble fiber, which helps lower cholesterol. Grains are also important sources of nutrients, carbohydrates, protein, and minerals. They are a significant source of energy for our bodies.

Spices and herbs

Spices and herbs are also important sources of fiber. Curry, cinnamon, oregano, coriander, and herbes de Provence provide more than 40 grams of fiber per 100 grams. They are rich in minerals, vitamins, and antioxidants such as polyphenols and curcumin, which protect the body against premature cell aging and the risk of certain cancers. Finally, they promote satiety and have anti-inflammatory properties. Don't hesitate to add them to your dishes.

Legumes

When cooked in water, legumes (red beans, white beans, lentils, etc.) contain an average of 15 grams of fiber per 100 grams. They are rich in vegetable protein, vitamins, and minerals such as iron, magnesium, phosphorus, and potassium. Legumes are commonly used as a partial substitute for meat in meat-free diets.

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Dried fruit

Nuts (almonds, hazelnuts, walnuts, pistachios, etc.) are also particularly rich in fiber, with an average content of 11 grams of fiber per 100 grams. They provide nutrients, healthy fats, vitamins, minerals, and antioxidants. Last but not least, they are associated with a reduction in cholesterol and the risk of cardiovascular disease. They are an excellent choice for snacks.

Fruits and vegetables

Finally, fruits and vegetables are significant sources of soluble and insoluble fiber. Among the vegetables richest in fiber are peas (5.5g/100g), spinach (3.5g/100g), green beans (3.3g/100g), celery (2.6g/100g), turnips (2.2g/100g), cauliflower (2g/100g) and, for fruit, raspberries (4.3g/100g), strawberries (3.8g/100g), apples (2.9g/100g), pears (2.9g/100g) and bananas (2.7g/100g). In addition to fiber, fruits and vegetables are also excellent sources of minerals and vitamins that are essential for the body.

Conclusion

In conclusion, fiber is a real health ally that is important to include in your diet. You should increase your intake gradually. However, you should not overdo it, as excess fiber can cause digestive problems such as flatulence, bloating, diarrhea, etc. It is therefore important to find the right balance.

Sources:

Dietary fiber. ANSES. Available at: https://agriculture.gouv.fr/sites/minagri/files/documents/pdf/Recommandation_GTFibres_VF_cle44b3dd.pdf

Ciqual. Food composition table. ANSES. Available at: https://ciqual.anses.fr/#/constituants/34100/fibres-alimentaires-(g-100-g)

Nutritional references for protein, fat, carbohydrates, and fiber (adults and seniors). CERIN. https://www.cerin.org/rapports/references-nutritionnelles-proteines-lipides-glucides-fibres-adultes-personnes-agees/

 

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